Observatory chief Rami Abdel Rahman added that few rebels were among the dead because they rarely left their tunnels and had better protection from air strikes than civilians, estimated to number around 400,000 in Ghouta.
Photo Rescue workers searched for survivors amid the rubble after airstrikes on the rebel-held town of Douma in the Eastern Ghouta suburbs.
He proposed adding language about a new investigative body to determine responsibility for chemical attacks that is unacceptable to the US and its allies.
Syria's President Bashar al-Assad is, with the support of Iranian-backed militias and the Russian air force, pursuing military offensives against insurgents in his opponents' last major strongholds in the west of the country.
Iran has also voiced opposition to the Turkish military operation in Syria, with President Hassan Rouhani saying on Tuesday that Ankara does not "have the permission of the [Syrian] government...and the consent of the people" for such an offensive.
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There has also been a spike in the number of reports of attacks by the government using chlorine as a chemical weapon, prompting warnings from the United States to the Syrian government to desist and to Russian Federation to pressure its ally to halt the attacks. His comments are yet another sign that is preparing to push its ongoing offensive against Syrian Kurds in the northwestern part of the country eastward, toward territory controlled by USA and coalition forces.
The following month, UNICEF says childhood malnutrition levels in the region are the highest recorded in Syria since the war began.
Among them was the young daughter of Abu Raad, a shell-shocked man from Eastern Ghouta.
The bombing was one of the bloodiest in the eastern Ghouta region for over a month.
In a statement Paulo Pinheiro said the spiralling violence in Syria had made "a mockery of the so-called "de-escalation zones" - an agreement a year ago between Russia, Iran, and Turkey to stabilise the lines of conflict and open corridors for urgently needed humanitarian relief.
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The global chemical weapons watchdog, the Organisation for the Prohibition of Chemical Weapons, expressed "grave concern" over the "credible allegations".
The use of any chemical weapons is a war crime, banned under the Geneva Convention.
Since the beginning of the year, the increase in violence in Idlib has resulted in another upsurge of internal displacement with over a quarter of a million civilians reportedly fleeing the fighting, according to reports received by the Commission.
The ceasefire should be "for at least one month" to allow for the delivery of humanitarian aid and the evacuation of the sick and wounded, the worldwide body said. Instead, the United Nations in Damascus this week said it has been unable to enter areas in need for two months. Almost five years later, more than 80 people were killed in another chemical attack on Khan Sheikhoun in Idlib province.
Meanwhile, the Syrian regime intercepted an Israeli attack on a military position in Jamraya, northwest of Damascus on Wednesday. If anything, there has been a serious escalation.
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James Acton, a nuclear weapons specialist at the Carnegie Endowment for International Peace, said that offer seems disingenuous. The new USA posture focuses heavily on what the administration sees as an overdue modernization of the nuclear arsenal.