Tutu added he was saddened that the allegations would tarnish the good work achieved by many thousands of people working for Oxfam.
In a statement released on Thursday afternoon, the archbishop says he's deeply disappointed by allegations of immorality and possible criminality involving humanitarian workers linked to the charity.
Aviol Fleurant, Haiti's minister of planning and external cooperation, said Oxfam officials had been summoned to meet with his ministry staff on Thursday to explain the sexual misconduct accusations allegedly perpetrated by the charity's employees in the wake of the devastating 2010 quake.
In his first response to the allegations of sexual misconduct, Roland Van Hauwermeiren said in an open letter to a broadcaster in his native Belgium he did not want to cast himself as a victim but feared that Oxfam, other charity workers and those they help would suffer from false accusations.
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"No organisation is too big, or our work with them too complex, for me to hesitate to remove funding from them if we can not trust them to put the beneficiaries of aid first", she said.
He said he had "intimate relations" with a Haitian woman but insisted that she was not a prostitute.
"I'm not a saint, I'm a man of flesh and blood and have made mistakes (not easy to admit), and I am deeply ashamed", he said.
He said he had never visited a brothel or nightclub in Haiti and audits had "never shown that funds were used to finance excesses or sex parties".
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As The Independent reports, Oxfam has also admitted that an aid worker sacked over alleged sexual misconduct in Haiti in 2011 was subsequently hired as a consultant in Ethiopia from October to December that year.
Complaining of "slander", he said he believed the reports were based on allegations by a man he had fired in Liberia for drunkenness and abusing staff. "I shall react... Many people, including in the global media, will blush hearing my version of facts", van Hauwermeiren was quoted as saying by the Het Nieuwsblad newspaper.
Reuters could not reach Van Hauwermeiren for direct comment.
She was due on Thursday to meet with law enforcement to discuss possible prosecution, following claims Oxfam workers paid for sex with prostitutes in Haiti, where prostitution is illegal, after the 2010 natural disaster.
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"Hiring him, even in an emergency as a short-term consultant, was a serious error and should never have happened", a statement said. The NCA has led past investigations into Britons who were convicted of sex crimes overseas.