The towering frontman scored standout efforts either side of half time to cancel out a leveller from Pepe, as Oscar Tabarez's charges turned in a memorable defensive showing to reach the last eight of the showpiece tournament. There was no goal from Ronaldo this time. Everywhere he went, the Portugal great was hounded by two or three Uruguayan defenders. Cavani switches the play with a handsome diagonal pass, which Suarez takes down. With that said, Rodrigo Bentancur soon restored the advantage as he laid on the second for Cavani.
"It's very exciting. I have no words to describe this", he told A Bola. Before he gave Ricardo Pereira any chance to close him down, Cavani placed a clinical first-time strike back across the goal and into the back of the net.
Guerreiro fired over from the edge of the box after a corner had fallen to him, and then Ronaldo laid the ball back to Adrien Silva, whose shot was deflected behind for a 55th-minute corner. It is Cristiano Ronaldo vs Diego Godin.
Messi's return in Russian Federation was more meagre - at times he looked disillusioned on the field as Argentine struggled to find anything like their usual style and he drifted deep into midfield in the forlorn hope of influencing games.
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Messi left wondering on the world stage again.
Portugal's loss means there will be no quarter-final showdown between Ronaldo and Lionel Messi, whose Argentina were knocked out by France earlier on Saturday. Godin is an expert at keeping clean sheets, as the leader of an Atletico defence that is the most formidable in the European club game - they kept 34 in all competitions last season - and of an Uruguay side that has not conceded a goal in 2018 in six games. Meanwhile, three of Portugal's last four goals have come from outside the box.
Clearly influenced by the methods of Diego Simeone at club level, the pair have been an impenetrable force throughout the tournament, although Pepe did find the net with the first goal Uruguay have conceded in Russian Federation to this point.
It was a five-pass buildup from deep in their own end that culminated in Uruguay's first goal, and the final two passes were ideal.
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Edinson Cavani latches onto the end of a Luis Suarez cross to nod in Uruguay's opener.
After huffing and puffing his way through the opening two group matches, Uruguay's talisman Edinson Cavani has finally arrived at the party, and in some style.
Messi provided two assists as Argentina were beaten in a thrilling match in Kazan but he has now appeared in the knockout stages of four World Cups and failed to score in any of them.
Stopping Ronaldo. It was that simple for Uruguay.
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