Portugal had fresh faith but Uruguay took just seven minutes to reassert their authority, Bentancur rolling a ball that Cavani swept into the far corner without breaking stride. Which means arguably two of the best footballers in the world will retire without helping their nation win a World Cup.
Cristiano Ronaldo went goalless, something his fans could not digest. "There is a fantastic group with enormous ambition that wants to succeed and I am very confident that the national team will continue to be at the highest level".
In his fourth World Cup, Ronaldo couldn't hide his frustration late in the match in Sochi, furiously complaining with the referee after a non-call for a foul that could have given Portugal a last chance to equalize. Uruguay, however, soon demonstrated their hunger to win, with Cavani's one-touch curler.
They had 61 percent possession, played more than double the number of passes as Uruguay and had 20 attempts compared to six from their opponents.
It took Portugal almost 60 minutes to answer, with a technically executed header by Pepe on 55 minutes following a high ball cross from the corner.
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Japan (4-2-3-1): Kawashima; Sakai, Shoji, Yoshida, Nagatomo; Hasebe, Shibasaki; Haraguchi, Kagawa, Inui; Osako. The win puts Belgium into the quarterfinals, setting up a mouth-watering clash with Brazil in the last-eight.
Tabarez said: 'When I walked out to the pitch I could hear our captain saying that we are playing for the father, the mother, the neighbour the brother and to give it your best.
Ronaldo won Euro 2016 with Portugal and has proven himself to be his country's greatest ever player.
"The truth is, it was really exciting", Cavani said. But he made a decision to give the ball to Cavani, who has scored three goals in Uruguay's last three matches, including two in the win over Portugal.
Ronaldo's Portugal met Uruguay for the first time in a World Cup and had to suffer the defeat, thanks to the brilliance of Cavani. "A group that has a big ambition to triumph and that is why I am happy about everything".
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The loss for Portugal against Uruguay ended the dream of legendary Cristiano Ronaldo, who alongside Argentina's Lionel Messi, may have to end a stellar worldwide career without the biggest trophy in football. "Even if he scores three goals in match, you still need to have a team to support him".
Cavani - hugging the touchline on the right wing - hit a brilliant crossfield pass to Suarez wide left.
Uruguay had eight blocked shot attempts after having just five in the first three games combined.
"Today we committed a mistake that led to the equaliser but we have a very strong team in terms of mindset", Tabarez added, citing the value of his team's "intensity, focus and tactical intuition".
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